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商品详细Signalchem/PFKFB1,有源/5 ug/P321-10G-05
Signalchem/PFKFB1,有源/5 ug/P321-10G-05
Signalchem/PFKFB1,有源/5 ug/P321-10G-05
商品编号: P321-10G-05
品牌: Signalchem inc
市场价: ¥5180.00
美元价: 3108.00
产地: 美国(厂家直采)
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产品分类: 聚合物
公司分类: juhewu
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商品介绍

Overview:

PFKFB1 is a member of the family of bifunctional 6-phosphofructo-2-kinase: fructose-2, 6-biphosphatase enzymes which forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains (1). Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Regulation of fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis (2).

Gene Aliases:

F6PK; HL2K; PFRX

Genbank Number:

NM_002625

References:

1. Algaier, J.et.al: Molecular cloning, sequence analysis, and expression of a human liver cDNA coding for fructose-6,2-kinase:fructose-2,6-bisphosphatase. Biochem. Biophys. Res. Commun. 153: 328-333, 1988.2. Darville, M. I. et.al: Complete nucleotide sequence coding for rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase derived from a cDNA clone. FEBS Lett. 224: 317-321, 1987.

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SignalChem 公司生产和销售创新性的细胞信号研究相关产品。公司专注于生产高纯度的活性重组蛋白,产品广泛应用于基础生物学和药物研究。
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