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商品详细Signalchem/FANCL Protein/20 ug/F289-30G-20
Signalchem/FANCL Protein/20 ug/F289-30G-20
Signalchem/FANCL Protein/20 ug/F289-30G-20
商品编号: F289-30G-20
品牌: Signalchem inc
市场价: ¥4300.00
美元价: 2580.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

FANCL or Fanconi anemia complementation group L is a member of the Fanconi anemia complementation group. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. FANCL is crucial in the FA pathway as the catalytic subunit required for monoubiquitination of FANCD2 (1). UBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2 (2).

Gene Aliases:

FAAP43; PHF9; POG

Genbank Number:

NM_018062

References:

1. Meetei.et.al: A novel ubiquitin ligase is deficient in Fanconi anemia. Nature Genet. 35: 165-170, 2003.2. Zhang, Y.et.al: UBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2. Molec. Cells 31: 113-122, 2011.

品牌介绍
SignalChem 公司生产和销售创新性的细胞信号研究相关产品。公司专注于生产高纯度的活性重组蛋白,产品广泛应用于基础生物学和药物研究。
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