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商品详细Signalchem/PRPF19 Protein/50 ug/P270-30G-50
Signalchem/PRPF19 Protein/50 ug/P270-30G-50
Signalchem/PRPF19 Protein/50 ug/P270-30G-50
商品编号: P270-30G-50
品牌: Signalchem inc
市场价: ¥8700.00
美元价: 5220.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
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商品介绍

Overview:

PRPF19 or pre-mRNA-processing factor 19 is the human homolog of yeast Pso4. PRPF19 is a gene essential for cell survival, DNA repair and association with terminal deoxynucleotidyl transferase (1). PRPF19 forms a stable complex with SETMAR (Metnase) which is a SET and transposase fusion protein in humans and plays a positive role in double-strand break (DSB) repair. PRPF19 mediates association of SETMAR with sites of DNA damage (2). SNEV is an orthologue of PRPF19 and is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.

Gene Aliases:

PSO4; SNEV; PRP19; UBOX4; hPSO4; NMP200

Genbank Number:

NM_014502

References:

1. Mahajan, K. N. et.al: Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase. Proc. Nat. Acad. Sci. 100: 10746-10751, 2003.2. Beck, B. D. et.al: Human Pso4 is a Metnase (SETMAR)-binding partner that regulates Metnase function in DNA repair. J. Biol. Chem. 283: 9023-9030, 2008.

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SignalChem 公司生产和销售创新性的细胞信号研究相关产品。公司专注于生产高纯度的活性重组蛋白,产品广泛应用于基础生物学和药物研究。
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