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商品详细Signalchem/MET(H1094Y),有效/10 ug/M52-12WG-10
Signalchem/MET(H1094Y),有效/10 ug/M52-12WG-10
Signalchem/MET(H1094Y),有效/10 ug/M52-12WG-10
商品编号: M52-12WG-10
品牌: Signalchem inc
市场价: ¥6500.00
美元价: 3900.00
产地: 美国(厂家直采)
公司:
产品分类: 激酶
公司分类: kinase
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商品介绍

Overview:

MET is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kDa (alpha) and 145 kDa (beta). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue (1). Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion (2).

Gene Aliases:

HGFR, RCCP2

Genbank Number:

NM_000245

References:

1. Giordano, S. et al: Biosynthesis of the protein encoded by the c-MET proto-oncogene. Oncogene. 1989 Nov;4(11):1383-8.2. Iyer, A. et al: Structure, tissue-specific expression, and transforming activity of the mouse MET protooncogene. Cell Growth Differ. 1990 Feb;1(2):87-95.

品牌介绍
SignalChem 公司生产和销售创新性的细胞信号研究相关产品。公司专注于生产高纯度的活性重组蛋白,产品广泛应用于基础生物学和药物研究。
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