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当前位置: 首页 > 产品中心 > RNA_enzymes > Signalchem/p38gamma siRNA组I/20 nmol/M37-911-20
商品详细Signalchem/p38gamma siRNA组I/20 nmol/M37-911-20
Signalchem/p38gamma siRNA组I/20 nmol/M37-911-20
Signalchem/p38gamma siRNA组I/20 nmol/M37-911-20
商品编号: M37-911-20
品牌: Signalchem inc
市场价: ¥24100.00
美元价: 14460.00
产地: 美国(厂家直采)
公司:
产品分类: RNA修饰酶
公司分类: RNA_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

p38 gamma is a member of the p38 MAPK family which is activated in response to stress (1). p38 gamma gene was mapped to 22q13.3 and functions as a signal transducer during differentiation of myoblasts to myotubes. Enforced localization of p38 gamma in the nucleus or cytoplasm markedly attenuates the ability of the kinase to induce cell cycle arrest in fibroblasts. p38 gamma increases basal glucose uptake and decreases DNP- and contraction-stimulated glucose uptake, partially by affecting levels of glucose transporter expression in skeletal muscle (2).

Gene Aliases:

ERK3; ERK6; SAPK3; PRKM12; MAPK12

Genbank Number:

NM_002969

References:

1. Li, Z. et al: The primary structure of p38-gamma: a new member of p38 group of MAP kinases. Biochem. Biophys. Res. Commun. 228: 334-340, 1996. 2. Ho, RC. et al: p38gamma MAPK regulation of glucose transporter expression and glucose uptake in L6 myotubes and mouse skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2004 Feb; 286(2):R342-9. Epub 2003 Oct 30.

品牌介绍
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