4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:活性激酶,信号蛋白,激酶抗体,非活性激酶,活性磷酸酶,生物相关激酶和多肽底物
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > juhewu > Signalchem/CYLD, Active/5 ug/C578-380G-05
商品详细Signalchem/CYLD, Active/5 ug/C578-380G-05
Signalchem/CYLD, Active/5 ug/C578-380G-05
Signalchem/CYLD, Active/5 ug/C578-380G-05
商品编号: C578-380G-05
品牌: Signalchem inc
市场价: ¥4520.00
美元价: 2712.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

CYLD is a cytoplasmic deubiquitinating enzyme, which removes ubiquitin molecules from various signaling proteins, and regulates the activities of many cellular and signaling processes. It plays a role in the regulation of inflammation, immunity, cell cycle progression, spermatogenesis, osteoclastogenesis, ciliogenesis, migration and tumorigenesis. (1) Several signaling pathways, such as the Nuclear Factor-kB (NF-kB), Wnt/β-catenin and c-Jun N-terminal kinase (JNK) pathways, and potentially others have been linked with or regulated by CYLD. (2) Mutations in CYLD gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. (3)

Gene Aliases:

EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2

Genbank Number:

NM_015247

References:

1. Bignell G.R. et al. Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet. 25(2):160–165, 2000.2. Verhoeft, K.R. et al The cylindromatosis (CYLD) gene and head and neck tumorigenesis. Cancers Head Neck. 1: 10, 2016. 3. EntreZ Gene: CYLD cylindromatosis (turban tumor syndrome)

品牌介绍
SignalChem 公司生产和销售创新性的细胞信号研究相关产品。公司专注于生产高纯度的活性重组蛋白,产品广泛应用于基础生物学和药物研究。
联络我们
服务热线:4000-520-616
(限工作日9:00-18:00)
QQ :1570468124
手机:18915418616