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商品详细Signalchem/Anti-AKT3/25 ug/A18-63R-25
Signalchem/Anti-AKT3/25 ug/A18-63R-25
Signalchem/Anti-AKT3/25 ug/A18-63R-25
商品编号: A18-63R-25
品牌: Signalchem inc
市场价: ¥2540.00
美元价: 1524.00
产地: 美国(厂家直采)
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产品分类: 聚合物
公司分类: juhewu
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商品介绍

Overview:

AKT 3 or Protein Kinase B (PKB ) is a serine/threonine kinase that is a member of the AKTγ (PKBγBfamily. AKT 3 is activated in cells exposed to diverse stimuli such as hormones, growth factors, and extracellular matrix components (1). AKT 3 phosphorylates and regulates the function of many cellular proteins involved in processes that include cellular metabolism, survival/apoptosis, and proliferation. Recent evidence indicates that AKT 3 is frequently overexpressed in many types of human cancers including breast and prostate (2).

References:

1. Coffer, PJ. et al: Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J. 1998 Oct 1; 335 (Pt 1): 1-13. 2. Anderson, KE. et al: Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B. Curr Biol. 1998 Jun 4;8(12): 684-91.

品牌介绍
SignalChem 公司生产和销售创新性的细胞信号研究相关产品。公司专注于生产高纯度的活性重组蛋白,产品广泛应用于基础生物学和药物研究。
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