4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:活性激酶,信号蛋白,激酶抗体,非活性激酶,活性磷酸酶,生物相关激酶和多肽底物
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > juhewu > Signalchem/RanGAP1蛋白质/20微克/R298-31H-20
商品详细Signalchem/RanGAP1蛋白质/20微克/R298-31H-20
Signalchem/RanGAP1蛋白质/20微克/R298-31H-20
Signalchem/RanGAP1蛋白质/20微克/R298-31H-20
商品编号: R298-31H-20
品牌: Signalchem inc
市场价: ¥4300.00
美元价: 2580.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

RANGAP1, Ran GTPase activating protein 1, is the control substrate, which produces a single SUMO modification during SUMOylation (1). As a GTPase activator, RANGAP1 is involved in nuclear envelope assembly and nuclear transport through interacting with Ras-related nuclear protein 1(RAN) and regulating GTP-binding and exchange (2). Also, abnormal localization of RanGAP1 was found in cortex of the patients with Huntington’s disease (3)

Gene Aliases:

Fug1; RANGAP; SD

Genbank Number:

NM_002883

References:

1. Joseph J., et.al. SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles. J. Cell Biol. 156:595-602, 2002.2. Swaminathan S., et.al. RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly. J. Cell Biol. 164:965-971, 2004.3. Gasset-Rosa F., et.al. Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport. Neuron. Apr 5; 94 (1):48-57, 2017.

品牌介绍
SignalChem 公司生产和销售创新性的细胞信号研究相关产品。公司专注于生产高纯度的活性重组蛋白,产品广泛应用于基础生物学和药物研究。
联络我们
服务热线:4000-520-616
(限工作日9:00-18:00)
QQ :1570468124
手机:18915418616